In the present work, comprehensive computational fluid dynamic (CFD) analysis has been carried out to observe the effect of flow induced vibration on the fuel toes of a typical research reactor. 2-D simulations have been carried out in the symmetry plane of inlet plenum of the research reactor to observe the wake formation inside and behind each fuel toe. Force coefficients have been calculated for all the fuel toes located in the symmetry plane. A relationship between Strouhal frequency and Reynolds number for the research reactor fuel toes has been established. The simulation was carried out in OpenFOAM-2.2.0 open source CFD code using pisoFoam solver. Validation of the computational procedure has been done by benchmarking the standard problem like flow past a circular cylinder and square cylinder at different Reynolds numbers. The velocity variation inside the fuel toes and the flow pattern are studied in detail using 2-D simulations. Keywords: Fuel toe, PisoFoam, Natural frequency, Forces and induced stresses.